Astudy revealed that thermosensory neurons of ectotherms affect lifespan at warm temperature by changing the activity of a steroid-signaling pathway that regulates longevity.Professor Seung-Jae Lee (Department of Life Science, School of Interdisciplinary Bioscience and Bioengineering, Division of IT Convergence Engineering) and his team, in collaboration with University of California, San Francisco, discovered that thermosensory neurons of C. elegans (Caenorhabditis elegans), an ectotherm, actively regulates the temperature dependence of lifespan.Many ectotherms, including C. elegans, have sho..
A team of multinational scientists developed a technique to produce tiny, nano-sized optical lenses, a breakthrough that may open new possibilities in microscopy and bio-imaging, the researchers said Wednesday. In a study published in peer-review journal Nature, the researchers, led by Kwang Kim, a researcher from the Pohang University of Science and Technology (POSTECH), said they found that cup-shaped organic molecules, called calyx hydroquinone (CHQ), self-assemble into a lens shape when placed on a surface. The nano-lenses produced in this way could push lens-based magnification to resolve..
Professor Kyo Han Ahn (Department of Chemistry) and his team, in a joint research with a Yonsei University group, have developed a new probe for mercury that can be used for imaging organs in living organisms.Mercury is a highly toxic and widespread pollutant, but the existing fluorescence probes for it mostly detected only its inorganic forms. The element is commonly found in organic forms which are much more toxic than inorganic mercury as their lipophilicity allows them to cross biological membranes. Consequently, new ways of detecting organic mercury species, particularly in organisms, was..
Professor Taihyun Chang (Department of Chemistry) and his group have developed toroidal micelles of uniform size from diblock copolymers.Block copoloymers can spontaneously self-assemble in a selective solvent to form micelles of various morphologies such as spherical micelles, cylindrical micelles, and vesicles. Recently, the variety of micellar shapes have been expanded to unconventional forms including toroids, tubes, disks, helices, and other complex forms.Although the toroid-shaped micelles have been reported earlier, the applicability of the toroid structure had been low due to the diffi..
In the Steven Spielberg movie A.I., robots not only resemble humans in looks but read their facial expressions, reacting accordingly. With the new technology developed by Professor Daijin Kim (Department of Computer Science and Engineering) and his group, the movie may soon become reality.Automatic expression analysis is difficult because people’s faces vary so much. Existing software could effectively recognize only extreme expressions, which is not particularly helpful in real-life situations. But the system developed by Professor Kim’s team recognizes even slight facial movement..
Mad cow disease made headlines in the early 2000s when 4.4 million cattle in the United Kingdom alone were killed as a precaution against it. Now, there may be a way to not only trace the disease in its incubation period but also medically treat it. Professor Daehee Hwang (School of Interdisciplinary Bioscience and Bioengineering) and his group, in collaboration with the Institute for Systems Biology (ISB), the McLaughlin Research Institute, the University of California, San Francisco, the Allen Brain Institute, and the European Bioinformatics Institute, have spotted a set of genes that go hay..
Korean scientists have identified the structure of a protein linked to epilepsy and other brain function abnormalities, which they say could present new opportunities in treatment and drug development. In a study published by peer-review European Molecular Biology Organization (EMBO) Journal, a team of researchers led Kim Kyung-jin of Pohang University of Science and Technology (POSTECH) presented the crystal structure of the succinic semialdehyde dehydrogenase (SSADH) protein. SSADH deficiency has been associated with epilepsy and other neurological conditions, and understanding the structure..
TGFβ ligands belonging to the Activin/Nodal family, induces mesoderm and endoderm, specifies the embryonic axes, promotes gastrulation movements, maintains pluripotency of embryonic stem cells, and determines left-right asymmetry in vertebrates. Activin/Nodal ligands signal through type I and type II transmembrane serine/threonine kinase receptors. Ligand binding induces the formation of heteromeric receptor complexes in which type II receptors phosphorylate and activate type I receptors. The activated type I receptors transduce the signal inside the cell through the phosphorylation of th..
Improvements in performance and reductions in cost of silicon-based nonvolatile memories, such as flash random access memory (flash-RAM), have rendered floppy discs and many other forms of portable storage obsolete. But for many uses that require data to be written only once, such as archiving and security applications, their cost effectiveness is limited. So-called write-onceread- many (WORM) memories made from low-cost polymer materials could provide a solution. The devices, developed by Professors Moonhor Ree, Ohyun Kim, Su-Moon Park and their research teams, are based on hyperbranched copp..
Professor Seung-Hoon Jhi and Ph.D. Candidate Seon-Myeong Choi, both of the Department of Physics, in their study of metal doped graphene nanoribbons, discovered that the adsorbed metal atoms form atomic chains which can be used as reagents to identify the edge atomic structures of the graphene nanoribbons and also as gate-driven spin valves to control the spin current in graphene nanoribbons. Graphene, the basic structural element of all graphitic materials including graphite, carbon nanotubes and fullerenes, is a one-atom-thick planar sheet of carbon atoms that are densely packed in a honeyco..